FP1247 : Analysis of Retinal Nerve Fiber Layer Thickness in Patients with Pseudoexfoliation Syndrome Using Spectral Domain Optical Coh

Dr. Nitish Arora, Dr. Roopa Naik, Dr. (Col) Rajendra Prasad Gupta, Dr. Snehal A Bhalsing

Aim : To detect early glaucomatous damage in PXS with normal IOP, visual field and optic nerve head appearance by assessing the RNFL thickness using OCT.

METHODS : A prospective observational study was carried out on 40 eyes; 20 non-glaucomatous eyes with PXS(group A) and 20 normal control subjects(group B). After informed consent was signed and BCVA, participants underwent slit lamp biomicroscopy, Goldmann applanation tonometry, gonioscopy, ophthalmoscopy, automated refraction and Humphrey(central 24-2 threshold) visual field.

RESULTS : This study demonstrated the mean overall RNFL thickness in both groups which was lower in group A than B.

CONCLUSION: PXS without glaucoma may be associated with a thinner RNFL compared with those of normal subjects. This provides evidence that structural damage preceeds functional loss and that early RNFL thickness assessment using OCT is important in the early diagnosis, intervention and follow-up of pseudo exfoliation glaucoma.

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