FP1323 : Efficacy of 5-Fluorouracil Bleb Needling for Failing or Encapsulated Blebs – A Long Term Study

Dr. A. Parivadhini, P17192, Dr. Wadke Vidya Arunkumar, Dr. George Ronnie J, Dr. Shantha Balekudaru

AIM:To study the long term efficacy of 5-Fluorouracil (5FU) bleb needling for failing filtering blebs.

METHODS:In this retrospective study,data from records of patients who underwent needling with 5FU with minimum follow-up of 6 months were analyzed. Absolute success was defined as intraocular pressure (IOP) of 5-18 mm Hg without antiglaucoma medications (AGM) and qualified success as IOP 5-18 mm Hg with AGM or additional needling procedure.

RESULTS:96 eyes were studied aged 6-79 years (median 50 years) ,majority (74) were male.There were 28 phakics,57 pseudophakics and 11 aphakes. Absolute success was achieved in 27 eyes (28%) and qualified success in 49 (51%) at final visit.The interval between trabeculectomy and needling was 0.37 to 1376 (mean 12.9) months and follow up was for 6.3 to 77.3 (mean 28.2) months.There were no late complications and no change in visual acuity post needling.

CONCLUSION:Needling with 5FU is a safe and effective procedure for treating failing blebs.


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