FP399 : Quantification of Fundus Autofluorescence in Diagnosis and Management of Ocular Toxoplasmosis

Priyansha Chatterjee,  C18819, Dr. Padmamalini Mahendradas, Dr. Ankush Kawali, Dr. Rohit Shetty

Aim: To measure autofluorescence changes in active and healed lesions of Ocular Toxoplasmosis

Methods: Retrospective interventional case series study of autofluorescence imaging with spectral domain optical coherence tomography (Heidelberg Spectralis). We manually measured the areas of hyper and hypo fluorescent lesions at presentation and follow ups.

Results: 8 eyes of 2 female and 5 male patients between the age group of 12-29 yrs with clinically diagnosed ocular toxoplasmosis, confirmed serologically were studied. 5 eyes mainly had hyper autofluorescent (AF) lesions at presentation (1-8μm) with small areas of hypo AF (0.6-8μm). All of them show decrease in hyper AF (1.4-6μm) on follow up correlating with clinical improvement and visual gain. 3 of them showed hypo AF lesions at presentation between (0.4-7μm) which reduced significantly (0.6-2μm) by last visit.

Conclusion:FAF can be used as an important noninvasive tool in monitoring the disease progression in Ocular Toxoplasmosis

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