FP449 : Ocular Syphilis: Characterizing the Great Masquerader

Dr.Ruchir Mehta, M13882, Dr. Padmamalini Mahendradas, Dr. Ankush Kawali, Dr. Rohit Shetty, Dr. Shetty Bhujang K

Purpose: To describe the clinical presentation and laboratory diagnosis of patients diagnosed with presumed ocular syphilis at a tertiary referral centre in southern India.

Methods: We reviewed the medical records of patients diagnosed with ocular syphilis from 2007-2016 at our hospital. Ocular syphilis was diagnosed on the basis of non-treponemal and treponemal antibody tests.

Results: 15 eyes of 10 patients were diagnosed with ocular syphilis based on the inclusion criteria. Only one of the patients was seropositive for HIV. Clinical presentations ranged from anterior uveitis to panuveitis. All of the patients showed clinical improvement in the level of ocular inflammation with intravenous/ intramuscular penicillin.

Conclusion: Ocular syphilis is not an uncommon entity in HIV-negative patients and it can present in many different ways. Treatment with systemic penicillin has shown improved disease outcome.

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